Nuremberg ( NURE-əm-burg; German: Nürnberg [ˈnʏʁnbɛʁk] (listen); in the local East Franconian dialect: Nämberch [ˈnɛmbɛrç]) is the second-largest city of the German state of Bavaria after its capital Munich, and its 518,370 (2019) inhabitants make it the 14th-largest city in Germany. On the Pegnitz River (from its confluence with the Rednitz in Fürth onwards: Regnitz, a tributary of the River Main) and the Rhine–Main–Danube Canal, it lies in the Bavarian administrative region of Middle Franconia, and is the largest city and the unofficial capital of Franconia. Nuremberg forms with the neighbouring cities of Fürth, Erlangen and Schwabach a continuous conurbation with a total population of 800,376 (2019), which is the heart of the urban area region with around 1.4 million inhabitants, while the larger Nuremberg Metropolitan Region has approximately 3.6 million inhabitants. The city lies about 170 kilometres (110 mi) north of Munich. It is the largest city in the East Franconian dialect area (colloquially: "Franconian"; German: Fränkisch).

There are many institutions of higher education in the city, including the University of Erlangen-Nuremberg (Friedrich-Alexander-Universität Erlangen-Nürnberg). With 39,780 students in 2017, it is Bavaria's third-largest and Germany's 11th-largest university, with campuses in Erlangen and Nuremberg and a university hospital in Erlangen (Universitätsklinikum Erlangen). Technische Hochschule Nürnberg Georg Simon Ohm and Hochschule für Musik Nürnberg are also located within the city. The Nuremberg exhibition centre (Messe Nürnberg) is one of the biggest convention center companies in Germany and operates worldwide. Nuremberg Airport (Flughafen Nürnberg "Albrecht Dürer") is the second-busiest airport in Bavaria after Munich Airport, and the tenth-busiest airport of the country.

Nuremberg Castle, with its many towers, is one of Europe's largest castles. Staatstheater Nürnberg is one of the five Bavarian state theatres, showing operas, operettas, musicals, and ballets (main venue: Nuremberg Opera House), plays (main venue: Schauspielhaus Nürnberg), as well as concerts (main venue: Meistersingerhalle). Its orchestra, the Staatsphilharmonie Nürnberg, is Bavaria's second-largest opera orchestra after the Bavarian State Opera's Bavarian State Orchestra in Munich. Nuremberg is the birthplace of Albrecht Dürer and Johann Pachelbel. 1. FC Nürnberg is the most famous football club of the city and one of the most successful football clubs in Germany. Nuremberg was one of the host cities of the 2006 FIFA World Cup.